Adjusted restricted mean survival times in observational studies
نویسندگان
چکیده
منابع مشابه
Double-robust semiparametric estimator for differences in restricted mean lifetimes in observational studies.
Restricted mean lifetime is often of direct interest in epidemiologic studies involving censored survival times. Differences in this quantity can be used as a basis for comparing several groups. For example, transplant surgeons, nephrologists, and of course patients are interested in comparing posttransplant lifetimes among various types of kidney transplants to assist in clinical decision maki...
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Causal inference in survival analysis has been centered on treatment effect assessment with adjustment of covariates. The direct adjustment method is usually employed to find the survival function of a treatment. A Cox model that stratifies the cumulative hazard by treatment is an ideal choice for performing direct adjustment because the treatment effects are allowed to vary over time. A SAS ma...
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For designing, monitoring and analyzing a longitudinal study with an event time as the outcome variable, the restricted mean event time (RMET) is an easily interpretable, clinically meaningful summary of the survival function in the presence of censoring. The RMET is the average of all potential event times measured up to a time point τ, which can be estimated consistently by the area under the...
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In this research we develop generalized linear regression models for the mean of a quality-of-life-adjusted restricted survival time. Parameter and standard error estimates could be obtained from generalized estimating equations applied to pseudo-observations. Simulation studies with moderate sample sizes are conducted and an example from the International Breast Cancer Study Group Ludwig Trial...
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ژورنال
عنوان ژورنال: Statistics in Medicine
سال: 2019
ISSN: 0277-6715,1097-0258
DOI: 10.1002/sim.8206